Detalhe da pesquisa
1.
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Cell
; 171(5): 1110-1124.e18, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033128
2.
IKKß primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Immunity
; 55(12): 2271-2284.e7, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36384135
3.
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
Immunity
; 54(4): 648-659.e8, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667383
4.
Human Monocytes Engage an Alternative Inflammasome Pathway.
Immunity
; 44(4): 833-46, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27037191
5.
GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis.
EMBO Rep
; 23(10): e54277, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35899491
6.
Therapeutic modulation of inflammasome pathways.
Immunol Rev
; 297(1): 123-138, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32770571
7.
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
EMBO J
; 33(24): 2937-46, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425575
8.
A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.
J Biol Chem
; 291(1): 103-9, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553871
9.
Structural basis for the oligomerization-facilitated NLRP3 activation.
Nat Commun
; 15(1): 1164, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326375
10.
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics.
Viruses
; 14(11)2022 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36366559
11.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
J Exp Med
; 216(7): 1700-1723, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31126966
12.
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1ß Maturation in Macrophages.
Cell Rep
; 25(9): 2354-2368.e5, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485805
13.
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum.
ACS Chem Biol
; 13(10): 2981-2988, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30183250